Changes in quality of life scale were trivial. After 6 months of growth hormone replacement therapy the psychological functioning improved significantly on mood scales (Profile of Mood State) and on a cognitive performance tests.
Growth hormone was administered in doses of 12 IU per week in an open design.
Eighteen adult patients with growth hormone deficiency syndrome were recruited to the study. The aim of this study was to investigate relationship between changes in mood, cognitive functioning, quality of life, changes in body composition and hormone concentration at baseline and six months after treatment with human recombinant growth hormone. Growth hormone replacement in adult growth hormone deficient patients improves psychological well-being and the quality of life.
